RAPIKACIN-500 is an injectable aminoglycoside antibiotic for treating serious gram-negative aerobic infections requiring hospital care and monitoring. Amikacin is a semisynthetic derivative of kanamycin with enhanced stability against bacterial aminoglycoside-modifying enzymes, providing potent activity against multidrug-resistant organisms including Pseudomonas aeruginosa, Acinetobacter baumannii, and ESBL-producing Enterobacteriaceae. This powerful antibiotic is reserved for severe infections where other agents have failed or resistance is suspected, necessitating careful dosing and monitoring to optimize efficacy while minimizing toxicity risks. This makes RAPIKACIN-500 an essential tool for healthcare providers managing complex infections in hospitalized patients, providing rapid and effective bacterial eradication while ensuring patient safety through its well-established pharmacokinetic and pharmacodynamic profile.
RAPIKACIN-500: Amikacin 500mg Injection for Serious Infections
Category: Injections
Packaging: 1x2ml Ampoule
Composition: Amikacin Sulphate IP 500mg per 2ml ampoule
Therapeutic Class: Antibiotic
Active Ingredient: Amikacin 500mg
Strength: 500mg per 2ml
MRP: ₹113.76
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Uses & Indications
- Serious gram-negative infections
- Hospital-acquired infections
- Pseudomonas infections
- Sepsis treatment
- Severe respiratory infections
Contraindications
- Myasthenia gravis
- Eighth cranial nerve disorder
Side Effects
The side effects listed below may occur with the use of this medication. However, not all individuals experience these effects.
- Ototoxicity (hearing loss)
- Nephrotoxicity (kidney damage)
- Neuromuscular blockade
- Rash
- Injection site reactions
Precautions
- Monitor kidney function
- IV or IM use only
- Peak-trough monitoring
Safety Advice & Precautions
- Requires close medical supervision
- Regular kidney function monitoring essential
- Auditory assessment recommended
- Maintain adequate hydration
- Not for prolonged use
- Contraindicated in myasthenia gravis
Storage Conditions
Store at temperature not exceeding 25°C. Protect from light.
Shelf Life & Expiry
36 months
Frequently Asked Questions
Strength 500?
500mg strength for systemic infections
Food effect?
Take on empty stomach for better absorption
Side effects common?
GI upset most common, report severe cases
Complete course?
Finish full course to prevent resistance
Medical Disclaimer
This product information is for educational purposes only. It is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always consult with a healthcare professional before starting any new medication or changing your dosage. Rapid Pharmaceuticals is not responsible for any adverse effects resulting from the misuse of this medication.
