ESMORIZE-D combines esomeprazole (S-isomer offering superior potency) with domperidone for comprehensive severe GERD management including Barrett's esophagus and refractory functional dyspepsia. The superior acid suppression combined with prokinetic action provides dramatic symptom improvement within 3-5 days for patients with sleep-disrupting nocturnal symptoms, reflux-related asthma, hoarseness, and chronic cough. This makes ESMORIZE-D an ideal choice for healthcare providers seeking a powerful and effective solution for managing severe GERD and associated complications in a single, convenient capsule form.



ESMORIZE-D: Esomeprazole + Domperidone for Severe GERD
Category: Capsules
Packaging: 10x10 Strip
Composition: Esomeprazole Magnesium IP 40mg (Enteric Coated) + Domperidone IP 30mg (Sustained Release)
Therapeutic Class: Gastrointestinal
Strength: 40mg + 30mg SR
MRP: ₹1100.00
Introduction
Uses & Indications
- Severe GERD symptoms
- Barrett's esophagus management
- Persistent dyspepsia
- Zollinger-Ellison syndrome
- Nausea and vomiting related to acid
Contraindications
- Perforation or obstruction
- Hypersensitivity
Side Effects
The side effects listed below may occur with the use of this medication. However, not all individuals experience these effects.
- Headache
- Diarrhea
- Bone pain (with long-term use)
- Rash
- C. difficile infection risk
Precautions
- Take 30 mins before meals
- Long-term monitoring required
- Do not crush capsule
Safety Advice & Precautions
- Take 30 minutes before meals
- Do not chew or crush capsule
- Long-term use may affect bone health
- Regular calcium and vitamin D intake recommended
- Monitor kidney function
- Report muscle pain or weakness
Storage Conditions
Store at temperature not exceeding 25°C. Protect from moisture.
Shelf Life & Expiry
24 months
Frequently Asked Questions
What is ESMORIZE-D used for?
ESMORIZE-D is used to treat Gastroesophageal Reflux Disease (GERD), acid acidity, heartburn, and associated nausea or vomiting.
When should I take ESMORIZE-D?
It is best taken 30 to 45 minutes before your first meal (breakfast) in the morning on an empty stomach.
Can I crush or chew the capsule?
No, the capsule should be swallowed whole with water. Crushing or chewing it will damage the enteric coating of the medicine.
Is it safe to take ESMORIZE-D long-term?
Long-term use should only be done under medical supervision, as it may affect magnesium or calcium absorption.
Medical Disclaimer
This product information is for educational purposes only. It is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always consult with a healthcare professional before starting any new medication or changing your dosage. Rapid Pharmaceuticals is not responsible for any adverse effects resulting from the misuse of this medication.




