SITARAP-M500 is a DPP-4 inhibitor and biguanide combination for effective type 2 diabetes management with good tolerability. Sitagliptin enhances insulin secretion and suppresses glucagon release, while metformin improves insulin sensitivity and reduces hepatic glucose production. This combination provides comprehensive glycemic control, weight neutrality, and potential beta cell function improvement, making SITARAP-M500 an ideal choice for patients with type 2 diabetes who require additional blood sugar control or have contraindications to other agents.
SITARAP-M500: Sitagliptin + Metformin for Diabetes Management
Category: Tablets
Packaging: 10x10 Alu Alu
Composition: Sitagliptin Phosphate Monohydrate IP 50mg + Metformin Hydrochloride IP 500mg (Sustained Release)
Therapeutic Class: Antidiabetic
Strength: 50mg + 500mg SR per tablet
MRP: ₹2400.00
SCHEDULE H PRESCRIPTION DRUG - WARNING:To be sold by retail on the prescription of a Registered Medical Practitioner only.
Request Info Introduction
Uses & Indications
- Type 2 diabetes management
- Blood glucose optimization
- Combination therapy initiation
- Weight neutral diabetes control
- Improved beta cell function
Contraindications
- Type 1 diabetes
- Severe renal impairment
- Acute infections
Side Effects
The side effects listed below may occur with the use of this medication. However, not all individuals experience these effects.
- Headache
- Upper respiratory infections
- Hypoglycemia (rare, with other agents)
- Gastrointestinal upset
- Pancreatitis (very rare)
Precautions
- Take with meals
- Do not crush SR tablet
- Monitor kidney function
Safety Advice & Precautions
- Take with meals
- Monitor blood glucose regularly
- Do not crush extended-release tablet
- Avoid alcohol consumption
- Report persistent headaches
- Regular kidney function tests recommended
Storage Conditions
Store at temperature not exceeding 25°C. Protect from moisture.
Shelf Life & Expiry
24 months
Frequently Asked Questions
How does SITARAP-M500 help with M500 combination?
Sitagliptin + Metformin 500mg
How does the dual mechanism of SITARAP-M500 help in glucose control?
Two routes to glucose control
Does taking SITARAP-M500 have any effect on body weight?
Usually weight neutral or loss
How does SITARAP-M500 help with Kidney function?
Monitor creatinine clearance regularly
Medical Disclaimer
This product information is for educational purposes only. It is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always consult with a healthcare professional before starting any new medication or changing your dosage. Rapid Pharmaceuticals is not responsible for any adverse effects resulting from the misuse of this medication.
